Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601807 | 0.93 | SREBF2 (0.48) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL29601262 | 0.81 | SMN1; SMN2 (0.54) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL22320128 | 0.78 | SMN1; SMN2 (0.54) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL30388055 | 0.73 | SREBF2 (0.51) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL29601797 | 0.71 | KMT2A (0.36) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL29601529 | 0.71 | MAPT (0.34) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL11213832 | 0.71 | RAB9A (0.77) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL29601747 | 0.68 | TGFBR1 (0.34) | SMN1; SMN2L3MBTL1ATMLMNAKDM4E | |
| SCHEMBL11533708 | 0.68 | RAB9A (0.66) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL11765529 | 0.67 | RAB9A (0.58) | SREBF2SMN1; SMN2RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232484-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087121-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-04-28 | — | — | WO | disclosed |