Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748192 | 0.87 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL29141633 | 0.87 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL28649101 | 0.85 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL30267526 | 0.85 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| Fumaric Acid SCHEMBL30911879 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL28857118 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL29600899 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL29538386 | 0.78 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL28558398 | 0.78 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL30748189 | 0.78 | TP53 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149412-A | Intermediate compound for preparing Vonoprazan | 鲁南制药集团股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-114149412-A | Intermediate compound for preparing Vonoprazan | 鲁南制药集团股份有限公司 | 2022-03-08 | — | — | CN | disclosed |