Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141637 | 1.00 | TP53 (0.40) | TP53GAANPC1RAB9ACHRNB2 | |
| SCHEMBL28649101 | 0.83 | CHRNB2 (0.41) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30267526 | 0.83 | CHRNB2 (0.41) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30267540 | 0.80 | ALDH1A1 (0.40) | TP53GAANPC1RAB9ACHRNB2 | |
| SCHEMBL28539151 | 0.80 | ALDH1A1 (0.40) | TP53GAANPC1RAB9ACHRNB2 | |
| SCHEMBL29601431 | 0.78 | CHRNB2 (0.42) | GAANPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL29141633 | 0.77 | CHRNB2 (0.40) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30748192 | 0.77 | CHRNB2 (0.40) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29538386 | 0.75 | CHRNB2 (0.38) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28558398 | 0.75 | CHRNB2 (0.38) | GAACHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448907-B | Compound for treating peptic ulcer, intermediate and preparation method thereof | 赛隆药业集团股份有限公司 | 2024-01-12 | — | — | CN | disclosed |