Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327324 | 0.83 | FGFR3 (0.50) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL28724019 | 0.82 | FGFR3 (0.51) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL24327827 | 0.77 | FGFR3 (0.53) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL29498949 | 0.76 | FGFR3 (0.56) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL24327350 | 0.76 | FGFR3 (0.56) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL24328692 | 0.76 | EPHB4 (0.40) | FGFR3AURKBMAPK1CHEK1CDK2 | |
| SCHEMBL24328703 | 0.75 | FGFR3 (0.51) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL24327370 | 0.75 | FGFR3 (0.51) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL24327347 | 0.74 | KDR (0.53) | KDRFGFR3CSF1RAURKBAURKA | |
| SCHEMBL29498933 | 0.74 | KDR (0.53) | KDRFGFR3CSF1RAURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |