Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327987 | 0.87 | LMNA (0.41) | EPHB4TEKKCNH2CCNKCCNA2 | |
| SCHEMBL24328691 | 0.81 | EPHB4 (0.46) | EPHB4TEKKCNH2NPBWR1FGFR2 | |
| SCHEMBL29498914 | 0.81 | EPHB4 (0.46) | EPHB4TEKKCNH2NPBWR1FGFR2 | |
| SCHEMBL29601464 | 0.76 | KDR (0.44) | FGFR3MAPK1CDK2CHEK1AURKB | |
| SCHEMBL24327773 | 0.75 | KCNH2 (0.55) | EPHB4TEKKCNH2NPBWR1FGFR2 | |
| SCHEMBL28724019 | 0.69 | FGFR3 (0.51) | KCNH2FGFR2FGFR3MAPK1CDK2 | |
| SCHEMBL24327879 | 0.67 | TEK (0.45) | EPHB4TEKKCNH2NPBWR1MAPK1 | |
| SCHEMBL24327401 | 0.67 | LRRK2 (0.45) | EPHB4TEKFGFR2FGFR3MAPK1 | |
| SCHEMBL24539466 | 0.67 | MAPK1 (0.41) | EPHB4TEKFGFR2FGFR3MAPK1 | |
| SCHEMBL24327324 | 0.66 | FGFR3 (0.50) | KCNH2FGFR2FGFR3MAPK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |