Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22583484 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL29601868 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL22583092 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29679633 | 0.71 | PPARG (0.38) | HPGDKDM4EALDH1A1ATF1NFKB1 | |
| SCHEMBL29435582 | 0.66 | KMT2A (0.37) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL22583033 | 0.66 | KMT2A (0.37) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL27669867 | 0.65 | KDM4E (0.48) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL2780020 | 0.65 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29028879 | 0.64 | HPGD (0.49) | MEN1KMT2AHPGDL3MBTL1KDM4E | |
| SCHEMBL22583237 | 0.63 | SMN1; SMN2 (0.40) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |