Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | IDO1 | P14902 | 1/20 | 1.00 |
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | TDO2 | P48775 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GSR | P00390 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374411 | 0.73 | HPGD (1.00) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL5009001 | 0.72 | HPGD (0.70) | HPGDKDM4EALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL30497266 | 0.71 | HPGD (0.62) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL11306203 | 0.71 | GSR (0.61) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL3471027 | 0.70 | TDP2 (0.62) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL3979773 | 0.69 | HPGD (0.62) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL18997336 | 0.68 | HPGD (0.65) | NSD2IDO1CRHBPTDO2CASP7 | |
| SCHEMBL9318535 | 0.68 | ALDH1A1 (0.60) | NSD2IDO1CRHBPTDO2CASP7 | |
| Hydrochloric Acid SCHEMBL7183276 | 0.68 | HPGD (0.68) | NSD2IDO1CRHBPTDO2CASP7 | |
| Hydrochloric Acid SCHEMBL7171387 | 0.68 | HPGD (0.68) | NSD2IDO1CRHBPTDO2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251569-A1 | TREATMENT AND PREVENTION OF DISEASE MEDIATED BY WWP2 | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-08-11 | — | — | US | disclosed |
| CN-114641571-A | Treatment and prevention of WWP2 mediated diseases | 新加坡国立大学 | 2022-06-17 | — | — | CN | disclosed |
| EP-3983544-A1 | TREATMENT AND PREVENTION OF DISEASE MEDIATED BY WWP2 | National University of Singapore (SG) | 2022-04-20 | — | — | EP | disclosed |