SCHEMBL29607908

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H]1CCCN1)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.69

▸	MAPK9	P45984	1/20	0.69

▸	MAPK10	P53779	1/20	0.69

▸	KEAP1	Q14145	1/20	0.58

▸	REN	P00797	12/20	0.56

▸	KDM1A	O60341	2/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29607286	0.96	MAPK8 (0.66)	MAPK8MAPK9MAPK10KEAP1REN
SCHEMBL29607801	0.96	MAPK8 (0.72)	MAPK8MAPK9MAPK10KEAP1REN
SCHEMBL29607530	0.94	MAPK8 (0.74)	MAPK8MAPK9MAPK10KEAP1REN
SCHEMBL29607872	0.90	MAPK8 (0.59)	MAPK8MAPK9MAPK10REN
SCHEMBL31232415	0.88	KEAP1 (0.67)	MAPK8MAPK9MAPK10KEAP1REN
SCHEMBL29607031	0.87	MAPK8 (0.61)	MAPK8MAPK9MAPK10REN
SCHEMBL29607740	0.86	MAPK8 (0.54)	MAPK8MAPK9MAPK10
SCHEMBL29608097	0.86	MAPK8 (0.61)	MAPK8MAPK9MAPK10KEAP1REN
SCHEMBL29607236	0.86	MAPK8 (0.61)	MAPK8MAPK9MAPK10REN
SCHEMBL29607270	0.85	MAPK8 (0.61)	MAPK8MAPK9MAPK10REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220120732-A1	TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES	RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL)	2022-04-21	—	—	US	disclosed