Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 3/20 | 0.59 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607286 | 0.92 | MAPK8 (0.66) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL29607908 | 0.88 | MAPK8 (0.69) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL30726561 | 0.87 | KEAP1 (0.68) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL31742423 | 0.86 | MAPK8 (0.69) | MAPK8MAPK9MAPK10REN | |
| SCHEMBL31182661 | 0.86 | F2 (0.65) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL29679520 | 0.85 | MAPK8 (0.65) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL29607801 | 0.85 | MAPK8 (0.72) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL30906548 | 0.85 | KEAP1 (0.72) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL31462013 | 0.84 | MAPK8 (0.59) | KEAP1MAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL29376375 | 0.84 | KEAP1 (0.60) | KEAP1MAPK8MAPK9MAPK10KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642492-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | claimed |
| WO-2024240173-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) | 2024-11-28 | — | — | WO | claimed |