Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23250267 | 1.00 | HDAC1 (0.35) | HDAC1HDAC6PDE3BPDE3AKDM1A | |
| SCHEMBL8847064 | 0.75 | ACHE (0.35) | HDAC1HDAC6ACHE | |
| SCHEMBL8909014 | 0.75 | CYP1A2 (0.38) | PDE3BPDE3ACYP1A2 | |
| SCHEMBL29863478 | 0.74 | CYP3A4 (0.32) | CYP1A2 | |
| SCHEMBL28341279 | 0.74 | RAPGEF4 (0.34) | KDM1AKDM1BACHE | |
| SCHEMBL23249000 | 0.74 | CYP3A4 (0.32) | CYP1A2 | |
| SCHEMBL356846 | 0.74 | TSHR (0.40) | PDE3BPDE3ACYP1A2 | |
| SCHEMBL19624709 | 0.72 | ALDH1A1 (0.33) | PDE3BPDE3ACYP1A2 | |
| Phosphine SCHEMBL27772308 | 0.72 | ACHE (0.33) | HDAC1HDAC6ACHE | |
| SCHEMBL16485488 | 0.72 | ACHE (0.33) | HDAC1HDAC6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192137-A | Inhibition of human integrin alpha4β7 | 莫菲克医疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-116783161-A | Inhibition of human integrin A4B7 | 莫菲克医疗股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4228634-A1 | INHIBITING HUMAN INTEGRIN A4B7 | Morphic Therapeutic, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081983-A1 | INHIBITING HUMAN INTEGRIN A4B7 | MORPHIC THERAPEUTIC, INC. (US) | 2022-04-21 | — | — | WO | disclosed |