Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 9/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313846 | 1.00 | METTL3 (0.49) | METTL3PRMT5WDR77ADORA3CHEK1 | |
| SCHEMBL24313688 | 0.92 | METTL3 (0.52) | METTL3PRMT5WDR77ADORA3MEN1 | |
| SCHEMBL29611650 | 0.92 | METTL3 (0.52) | METTL3PRMT5WDR77ADORA3MEN1 | |
| SCHEMBL29610818 | 0.91 | ADORA3 (0.40) | METTL3PRMT5WDR77ADORA3METTL14 | |
| SCHEMBL24313535 | 0.91 | ADORA3 (0.40) | METTL3PRMT5WDR77ADORA3METTL14 | |
| SCHEMBL24313687 | 0.90 | METTL3 (0.39) | METTL3PRMT5WDR77ADORA3METTL14 | |
| SCHEMBL29611149 | 0.90 | METTL3 (0.39) | METTL3PRMT5WDR77ADORA3METTL14 | |
| SCHEMBL24313841 | 0.88 | METTL3 (0.40) | METTL3PRMT5WDR77ADORA3 | |
| SCHEMBL29611544 | 0.88 | METTL3 (0.40) | METTL3PRMT5WDR77ADORA3 | |
| SCHEMBL24313534 | 0.85 | METTL3 (0.58) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |