Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1685534 | 1.00 | GABRA1 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Fluoride Ion SCHEMBL7639206 | 0.97 | GABRA1 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL8823402 | 0.86 | GABRA1 (0.31) | GABRA1GABRB2FABP4FABP3 | |
| Hydrochloric Acid SCHEMBL8636157 | 0.83 | METAP2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6523108 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27477259 | 0.80 | GABRA1 (0.31) | GABRA1GABRB2FABP4FABP3 | |
| Hydrochloric Acid SCHEMBL8632959 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2529411 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL9421533 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL5583459 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2FABP4FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | claimed |
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | disclosed |