Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27497577 | 0.85 | HTR2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL27512802 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL5619189 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL27463390 | 0.80 | GABRA1 (0.34) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL9421533 | 0.80 | GABRA1 (0.34) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL8535091 | 0.80 | GABRA1 (0.32) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL1685534 | 0.79 | GABRA1 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL29612295 | 0.79 | GABRA1 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL27478549 | 0.79 | FABP4 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| Hydrochloric Acid SCHEMBL27496568 | 0.78 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | claimed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | claimed |
| EP-0859800-B1 | SUPPORTED CATALYST SYSTEM, PROCESS FOR ITS PRODUCTION AND ITS USE IN POLYMERISING OLEFINES | BASELL POLYOLEFINE GMBH (DE) | 2003-07-23 | — | — | EP | claimed |
| EP-0842205-B1 | IMPROVED METHOD FOR PREPARING METALLOCENE CATALYST SYSTEMS | EXXON CHEMICAL PATENTS INC (US) | 2001-02-14 | — | — | EP | claimed |
| CN-1130912-A | Supported metallocene catalyst systems for polymerization of olefins, preparation and use thereof | EXXON CHEMICAL PATENTS INC (US) | 1996-09-11 | — | — | CN | claimed |
| CN-116199813-A | Long chain branched polypropylene and preparation method thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-101384624-B | Catalyst composition for olefin polymerization | NOVOLEN TECH HOLDINGS CV | 2012-07-04 | — | — | CN | disclosed |
| CN-101316871-B | Moulding composition comprising polyethylene for producing films and method for producing said moulding composition in the presence of a mixed catalyst | BASELL POLYOLEFINE GMBH | 2011-06-01 | — | — | CN | disclosed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | disclosed |
| CN-101511879-A | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEM PATENTS INC (US) | 2009-08-19 | — | — | CN | disclosed |
| CN-101384624-A | Catalyst composition for olefin polymerization | NOVOLEN TECH HOLDINGS CV (NL) | 2009-03-11 | — | — | CN | disclosed |
| EP-0705281-B1 | SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF | EXXON CHEMICAL PATENTS INC (US) | 1998-03-11 | — | — | EP | disclosed |
| CN-1160055-A | Process for reducing by-product in product mixture | HOECHST AG (DE) | 1997-09-24 | — | — | CN | disclosed |
| EP-0739346-A1 | USE OF GEL-FREE ALUMOXANE SOLUTION | EXXON CHEMICAL PATENTS INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| CN-1130912-A | Supported metallocene catalyst systems for polymerization of olefins, preparation and use thereof | EXXON CHEMICAL PATENTS INC (US) | 1996-09-11 | — | — | CN | disclosed |
| CN-1107162-A | Metallocen method for preparation of same and application of same as catalyst | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| WO-1995018809-A1 | USE OF GEL-FREE ALUMOXANE SOLUTION | EXXON CHEMICAL PATENTS INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| US-5374752-A | Catalyst system containing metallocene | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | disclosed |
| US-5328969-A | Cocatalyst of an aluminoxane and metallocene | HOECHST AKTIENGELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |