Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042317 | 0.87 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL29612541 | 0.83 | CNR2 (0.39) | DGAT1 | |
| SCHEMBL28730693 | 0.83 | CNR2 (0.39) | DGAT1 | |
| SCHEMBL23042580 | 0.80 | THRB (0.48) | THRATHRB | |
| SCHEMBL23042328 | 0.78 | MEN1 (0.34) | THRATHRB | |
| SCHEMBL23042331 | 0.78 | MEN1 (0.34) | THRATHRB | |
| SCHEMBL29729433 | 0.77 | MEN1 (0.44) | THRATHRB | |
| SCHEMBL28730644 | 0.77 | MEN1 (0.44) | THRATHRB | |
| SCHEMBL23042334 | 0.76 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL29729388 | 0.75 | THRA (0.46) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |