SCHEMBL29612557

SCHEMBL29612557

Cc1n[nH]c2ccc(Oc3c(Cl)cc(-n4ncc(=O)[nH]c4=O)cc3Cl)cc12

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 20/20 0.53
THRA P10827 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612491 0.87 THRB (0.52) THRBTHRA
SCHEMBL24781755 0.82 THRB (0.63) THRBTHRA
SCHEMBL23042577 0.80 THRA (0.57) THRBTHRA
SCHEMBL6219582 0.80 NPBWR1 (0.59) THRBTHRA
SCHEMBL9502425 0.78 THRB (0.82) THRBTHRA
SCHEMBL6213829 0.77 THRB (0.64) THRBTHRA
SCHEMBL6214724 0.77 THRB (0.62) THRBTHRA
SCHEMBL9503278 0.77 THRB (0.59) THRBTHRA
SCHEMBL30460708 0.76 THRB (0.53) THRBTHRA
SCHEMBL9501104 0.76 THRB (0.60) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114430743-A Thyroid hormone receptor beta agonist compounds 拓臻制药公司 2022-05-03 CN disclosed