Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.63 |
| ▸ | TOP2A | P11388 | 3/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3510262 | 1.00 | TERT (0.63) | TERTTOP2ANQO1GSK3AGSK3B | |
| SCHEMBL2967645 | 0.89 | NQO1 (0.63) | TERTTOP2ANQO1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL3508543 | 0.88 | PAX8 (0.64) | TERTTOP2ANQO1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL3511768 | 0.82 | TERT (0.60) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL2965102 | 0.82 | NQO1 (0.55) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL13243586 | 0.82 | UTS2R (0.60) | NQO1GSK3AGSK3BPAX8POLB | |
| Hydrochloric Acid SCHEMBL3510900 | 0.81 | PAX8 (0.56) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL27199814 | 0.80 | CSNK2A1 (0.48) | TERTTOP2ANQO1GSK3AGSK3B | |
| SCHEMBL3508559 | 0.78 | DYRK1A (0.56) | TERTNQO1GSK3AGSK3BPAX8 | |
| Hydrochloric Acid SCHEMBL3509482 | 0.78 | TERT (0.52) | TERTNQO1GSK3AGSK3BPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122668-A1 | COMBINED INHIBITION OF AMINO ACID TRANSPORTERS FOR INHIBITING HUMAN PLASMACYTOID DENDRITIC CELL ACTIVITY DURING AUTOIMMUNITY | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-06-16 | — | — | WO | claimed |
| EP-4008330-A1 | COMBINED INHIBITION OF AMINO ACID TRANSPORTERS FOR INHIBITING HUMAN PLASMACYTOID DENDRITIC CELL ACTIVITY DURING AUTOIMMUNITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-06-08 | — | — | EP | claimed |
| WO-2022122668-A1 | COMBINED INHIBITION OF AMINO ACID TRANSPORTERS FOR INHIBITING HUMAN PLASMACYTOID DENDRITIC CELL ACTIVITY DURING AUTOIMMUNITY | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-06-16 | — | — | WO | disclosed |
| EP-4008330-A1 | COMBINED INHIBITION OF AMINO ACID TRANSPORTERS FOR INHIBITING HUMAN PLASMACYTOID DENDRITIC CELL ACTIVITY DURING AUTOIMMUNITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-06-08 | — | — | EP | disclosed |