Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3510900 | 0.99 | PAX8 (0.56) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| SCHEMBL2967645 | 0.86 | NQO1 (0.63) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| Hydrochloric Acid SCHEMBL3509482 | 0.85 | TERT (0.52) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| Hydrochloric Acid SCHEMBL3508543 | 0.85 | PAX8 (0.64) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| Hydrochloric Acid SCHEMBL3511768 | 0.84 | TERT (0.60) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| SCHEMBL13243586 | 0.84 | UTS2R (0.60) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| SCHEMBL29615014 | 0.82 | TERT (0.63) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| SCHEMBL3510262 | 0.82 | TERT (0.63) | NQO1GSK3AGSK3BPAX8DYRK1A | |
| SCHEMBL13243587 | 0.80 | NQO1 (0.47) | NQO1GSK3AGSK3BPAX8TERT | |
| SCHEMBL2969441 | 0.79 | EGFR (0.52) | NQO1GSK3AGSK3BPAX8DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763633-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-07-27 | — | — | US | disclosed |
| US-7763633-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-07-27 | — | — | US | disclosed |
| US-7763633-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-07-27 | — | — | US | disclosed |
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-12-03 | — | — | US | disclosed |
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-12-03 | — | — | US | disclosed |
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298846-A1 | Indolo[3,2-c]quinoline Compounds | TERT, TERF2, CDKN1A | NQO1 75/4885GSK3A 1875/4885GSK3B 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.