Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.63 |
| ▸ | TOP2A | P11388 | 3/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615014 | 1.00 | TERT (0.63) | TERTTOP2ANQO1GSK3AGSK3B | |
| SCHEMBL2967645 | 0.89 | NQO1 (0.63) | TERTTOP2ANQO1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL3508543 | 0.88 | PAX8 (0.64) | TERTTOP2ANQO1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL3511768 | 0.82 | TERT (0.60) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL2965102 | 0.82 | NQO1 (0.55) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL13243586 | 0.82 | UTS2R (0.60) | NQO1GSK3AGSK3BPAX8POLB | |
| Hydrochloric Acid SCHEMBL3510900 | 0.81 | PAX8 (0.56) | TERTNQO1GSK3AGSK3BPAX8 | |
| SCHEMBL27199814 | 0.80 | CSNK2A1 (0.48) | TERTTOP2ANQO1GSK3AGSK3B | |
| SCHEMBL3508559 | 0.78 | DYRK1A (0.56) | TERTNQO1GSK3AGSK3BPAX8 | |
| Hydrochloric Acid SCHEMBL3509482 | 0.78 | TERT (0.52) | TERTNQO1GSK3AGSK3BPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273760-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-09-25 | — | — | US | disclosed |
| US-8273760-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-09-25 | — | — | US | disclosed |
| US-8273760-B2 | Indolo[3,2-c]quinoline compounds | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-09-25 | — | — | US | disclosed |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | Kaohsiung Medical Univeristy (TW) | 2010-11-11 | — | — | US | disclosed |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | Kaohsiung Medical Univeristy (TW) | 2010-11-11 | — | — | US | disclosed |
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | Kaohsiung Medical Univeristy (TW) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286163-A1 | INDOLO[3,2-C]QUINOLINE COMPOUNDS | TERT, INMT, TERF2 | TERT 1/4885TOP2A 47/4885NQO1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.