Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 8/20 | 0.44 |
| ▸ | FNTB | P49356 | 8/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615137 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL4227222 | 0.91 | KMT2A (0.48) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL4227234 | 0.91 | KMT2A (0.48) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL30525295 | 0.90 | DPP4 (0.55) | DPP4DPP8DPP9NOD1KMT2A | |
| SCHEMBL30591036 | 0.87 | DPP4 (0.52) | DPP4DPP8DPP9NOD1KMT2A | |
| SCHEMBL7071336 | 0.87 | FOLH1 (0.47) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL7071333 | 0.87 | FOLH1 (0.47) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL29615104 | 0.86 | FNTA (0.51) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL29615086 | 0.86 | FNTA (0.51) | DPP4DPP8DPP9NOD1FNTA | |
| SCHEMBL30193412 | 0.86 | FOLH1 (0.47) | DPP4DPP8DPP9NOD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-12285460-B2 | Pharmaceutical compositions | RHYTHM PHARMACEUTICALS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | PCTP, SLC27A1, CETP | DPP4 2850/4885DPP8 3441/4885DPP9 2683/4885 |
| US-12285460-B2 | Pharmaceutical compositions | PCTP, SLC27A1, CETP | DPP4 2850/4885DPP8 3441/4885DPP9 2683/4885 |
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | ARGLU1, FFAR3, ASNS | DPP4 1288/4885DPP8 773/4885DPP9 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.