Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.59 |
| ▸ | KISS1R | Q969F8 | 6/20 | 0.52 |
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895432 | 0.94 | GHSR (0.53) | GHSR | |
| SCHEMBL31001649 | 0.93 | GHSR (0.57) | GHSRKISS1RMC4R | |
| SCHEMBL30866229 | 0.93 | GHSR (0.67) | GHSRKISS1R | |
| SCHEMBL31606511 | 0.90 | GHSR (0.59) | GHSRKISS1RMC4R | |
| SCHEMBL30866241 | 0.90 | GHSR (0.62) | GHSRKISS1R | |
| SCHEMBL30866204 | 0.90 | GHSR (0.63) | GHSRKISS1RIL23R | |
| SCHEMBL30544299 | 0.88 | GHSR (0.53) | GHSRKISS1RIL23R | |
| SCHEMBL30544310 | 0.88 | GHSR (0.58) | GHSRKISS1R | |
| SCHEMBL30866231 | 0.88 | GHSR (0.57) | GHSRKISS1RMC4R | |
| SCHEMBL29994188 | 0.88 | GHSR (0.57) | GHSRKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-12285460-B2 | Pharmaceutical compositions | RHYTHM PHARMACEUTICALS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | PCTP, SLC27A1, CETP | GHSR 680/4885KISS1R 2149/4885MC4R 268/4885 |
| US-12285460-B2 | Pharmaceutical compositions | PCTP, SLC27A1, CETP | GHSR 680/4885KISS1R 2149/4885MC4R 268/4885 |
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | ARGLU1, FFAR3, ASNS | GHSR 322/4885KISS1R 2023/4885MC4R 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.