Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4218173 | 0.98 | HSPB1 (0.64) | HSPB1POLBCA12CA1CA2 | |
| SCHEMBL7026994 | 0.93 | HSPB1 (0.75) | HSPB1POLBCA12CA1CA2 | |
| SCHEMBL536 | 0.93 | HSPB1 (0.75) | HSPB1POLBCA12CA1CA2 | |
| Fluoride SCHEMBL4551986 | 0.90 | HSPB1 (0.72) | HSPB1POLBLMNAMAPTKCNJ1 | |
| Water SCHEMBL28147677 | 0.90 | HSPB1 (0.72) | HSPB1POLBLMNAMAPTKCNJ1 | |
| SCHEMBL28001935 | 0.90 | HSPB1 (0.72) | HSPB1POLBLMNAMAPTKCNJ1 | |
| Fluoride SCHEMBL4551988 | 0.90 | HSPB1 (0.72) | HSPB1POLBLMNAMAPTKCNJ1 | |
| Formaldehyde SCHEMBL28237406 | 0.88 | HSPB1 (0.69) | HSPB1POLBLMNAMAPTKCNJ1 | |
| Ethylene SCHEMBL27864908 | 0.88 | HSPB1 (0.69) | HSPB1POLBLMNAMAPTKCNJ1 | |
| Ethane SCHEMBL28251595 | 0.88 | HSPB1 (0.69) | HSPB1POLBLMNAMAPTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219454-A | Method for preparing aromatic nitrile compound by photoinitiating nitroarene denitration cyanation | 武汉光化学技术研究院 | 2024-12-31 | — | — | CN | disclosed |
| WO-2017202772-A1 | FLUORINATED POLYMERS COMPRISING AROMATIC END GROUPS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2017-11-30 | — | — | WO | disclosed |
| US-7772446-B2 | Method for producing substituted biphenyls | BASF SE (DE) | 2010-08-10 | — | — | US | disclosed |
| EP-1856024-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2008-07-31 | — | — | US | disclosed |
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | disclosed |
| US-6362380-B1 | REACTING 2-NITROCHLOROBENZENE AND A BORONIC ACID ; PALLADIUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-0888261-B1 | PROCESS FOR PREPARING NITROBIPHENYLENE | BASF AG (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-4913844-A | ISOTROPIC; TRANSPARENT OPTICAL COMPONENTS IN LIGHT SWITCHES AND MODULATORS | HOECHST CELANESE CORP. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0332851-A1 | Condensation polymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4867540-A | Condensation polymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0328268-A1 | Acrylic polymers and copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0321891-A2 | Bisacrylate monomers and polymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4826950-A | Condensation polymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4196215-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4115456-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-19 | — | — | US | disclosed |
| US-4044049-A | Phenyl benzoic acid compounds | MERCK & CO., INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | CBR3, DDT, HRH3 | HSPB1 2101/4885POLB 1232/4885CA12 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.