Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23149068 | 1.00 | GRM5 (0.45) | GRM5CHRM1CHRM3NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29616565 | 0.73 | CHRM1 (0.47) | GRM5CHRM1CHRM3NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL23148960 | 0.73 | CHRM1 (0.47) | GRM5CHRM1CHRM3NPC1RAB9A | |
| SCHEMBL30488782 | 0.69 | CPT2 (0.48) | TSHRL3MBTL1POLBLMNACASP3 | |
| SCHEMBL25290141 | 0.69 | CPT2 (0.48) | TSHRL3MBTL1POLBLMNACASP3 | |
| SCHEMBL6781064 | 0.66 | CHRM2 (0.53) | CHRM1TSHRNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21889030 | 0.66 | AOC3 (0.54) | CHRM1CHRM3NPC1RAB9ATP53 | |
| SCHEMBL7396263 | 0.66 | NPC1 (0.52) | CHRM1CHRM3NPC1RAB9AHPGD | |
| SCHEMBL25254795 | 0.64 | NPSR1 (0.32) | TP53NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6980247 | 0.64 | ALDH1A1 (0.40) | CHRM1CHRM3HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401968-A | Novel heterocyclic monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-26 | — | — | CN | disclosed |