SCHEMBL388604

SCHEMBL388604

CC(=O)NC(=O)C(N)CS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGS2 P35354 1/20 0.39
THPO P40225 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CRBN Q96SW2 1/20 0.39
MMP2 P08253 1/20 0.38
SLC15A1 P46059 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TAS2R38 P59533 1/20 0.36
ENPEP Q07075 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388605 1.00 PTGS1 (0.46) PTGS1SLC7A11KDM4EMAPTTHRB
Cysteamine SCHEMBL28277491 0.92 PTGS1 (0.40) PTGS1SLC7A11KDM4EMAPTTHRB
SCHEMBL8352097 0.85 PTGS1 (0.55) PTGS1SLC7A11MMP2SLC15A1CA12
SCHEMBL28400301 0.84 KDM4E (0.37) PTGS1SLC7A11KDM4EMAPTTHRB
Diacetamide SCHEMBL28020314 0.80 PTGS1 (0.70) PTGS1SLC7A11KDM4EMAPTTHRB
SCHEMBL11888829 0.79 CRBN (0.40) KDM4EMAPTPTGS2THPOCRBN
SCHEMBL29019106 0.79 PTGS1 (0.54) PTGS1SLC7A11MMP2SLC15A1CA12
SCHEMBL29616775 0.79 CRBN (0.40) KDM4EMAPTPTGS2THPOCRBN
SCHEMBL28240743 0.79 PTGS1 (0.54) PTGS1SLC7A11MMP2SLC15A1CA12
SCHEMBL14725064 0.79 SLC15A1 (0.42) CRBNSLC15A1CA1CA2TAS2R38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12350283-B2 Methods and compositions for treating motor neuron diseases UNIVERSITAT DE VALENCIA-ESTUDI GENERAL (ES) 2025-07-08 US claimed
EP-4093389-A1 PRODRUG FOR THE TREATMENT OF DISEASE AND INJURY OF OXIDATIVE STRESS NaCuity Pharmaceuticals, Inc. (US) 2022-11-30 EP claimed
US-20220160745-A1 METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES UNIVERSITAT DE VALÈNCIA-ESTUDI GENERAL (ES) 2022-05-26 US claimed
EP-3842040-B1 METHODS AND FORMULATIONS FOR TREATMENT OF AND/OR PROTECTION AGAINST ACUTE LIVER FAILURE AND OTHER HEPATOTOXIC CONDITIONS EGETIS THERAPEUTICS AB (SE) 2022-03-09 EP claimed
EP-3930728-A1 METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES Universitat de Valencia - Estudi General (ES) 2022-01-05 EP claimed
EP-3402475-B1 METHODS AND FORMULATIONS FOR TREATMENT OF AND/OR PROTECTION AGAINST ACUTE LIVER FAILURE AND OTHER HEPATOTOXIC CONDITIONS EGETIS THERAPEUTICS AB (SE) 2021-10-20 EP claimed
WO-2021151044-A1 PRODRUG FOR THE TREATMENT OF DISEASE AND INJURY OF OXIDATIVE STRESS NACUITY PHARMACEUTICALS, INC. (US) 2021-07-29 WO claimed
EP-3122342-B1 METHOD FOR THE PREPARATION OF N-ACETYL CYSTEINE AMIDE NACUITY PHARMACEUTICALS INC (US) 2020-09-23 EP claimed
EP-3019164-B1 USE OF N-ACETYLCYSTEINE AMIDE IN THE TREATMENT OF PENETRATING HEAD INJURY GOLDSTEIN GLENN A (US) 2020-08-19 EP claimed
EP-2976061-B1 COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS DENTALMED PHARM HOLDING LTD (BE) 2019-10-16 EP claimed
EP-2841064-B1 USE OF N-ACETYLCYSTEINE AMIDE IN THE TREATMENT OF CATARACTS SENTIENT LIFESCIENCES INC (US) 2019-06-12 EP claimed
EP-2976061-A1 COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS Dentalmed Pharm Holding Ltd. (BE) 2016-01-27 EP claimed
WO-2014147613-A1 COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS DENTALMED PHARM HOLDING LTD. (BE) 2014-09-25 WO claimed
US-12617747-B2 Cannabinoid analogs and methods for their preparation INMED PHARMACEUTICALS INC. (CA) 2026-05-05 US disclosed
EP-4469044-B1 IONIC-LIQUID-BASED FORMULATIONS FOR THE PREVENTION OR TREATMENT OF NEUROLOGICAL DISEASES UNIV AVEIRO (PT) 2026-04-08 EP disclosed
US-12514845-B2 Ionic-liquid-based formulations for the prevention or treatment of neurological diseases UNIVERSIDADE DE AVEIRO (PT) 2026-01-06 US disclosed
EP-2976061-A1 COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS Dentalmed Pharm Holding Ltd. (BE) 2016-01-27 EP disclosed
WO-2014147613-A1 COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS DENTALMED PHARM HOLDING LTD. (BE) 2014-09-25 WO disclosed
EP-2408441-A1 COMBINATION THERAPIES FOR TREATING METABOLIC DISORDERS Genmedica Therapeutics SL (ES) 2012-01-25 EP disclosed
WO-2010106083-A1 COMBINATION THERAPIES FOR TREATING METABOLIC DISORDERS GENMEDICA THERAPEUTICS SL (ES) 2010-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617747-B2 Cannabinoid analogs and methods for their preparation CNR2, CNR1, FAAH PTGS1 2647/4885SLC7A11 4463/4885KDM4E 2119/4885
US-20220160745-A1 METHODS AND COMPOSITIONS FOR TREATING MOTOR NEURON DISEASES SMN1; SMN2, NNMT, PDE4A PTGS1 67/4885SLC7A11 436/4885KDM4E 1642/4885
US-12350283-B2 Methods and compositions for treating motor neuron diseases SMN1; SMN2, NNMT, PDE4A PTGS1 67/4885SLC7A11 436/4885KDM4E 1642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.