SCHEMBL29617535

SCHEMBL29617535

CC(C)(O)[C@H]1CC=CCC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CES2 O00748 2/20 0.41
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3316886 1.00 LMNA (0.45) LMNACES2ALDH1A1ALOX15
SCHEMBL25239151 0.82
SCHEMBL455930 0.80 ALDH1A1 (0.36) ALDH1A1ALOX15
SCHEMBL3549870 0.80 ALDH1A1 (0.36) ALDH1A1ALOX15
SCHEMBL9926598 0.79 NR1H2 (0.30)
SCHEMBL23319668 0.77 CES2 (0.35) LMNACES2ALDH1A1
SCHEMBL2827222 0.74 CES2 (0.33) LMNACES2ALDH1A1ALOX15
SCHEMBL91212 0.73 ALDH1A1 (0.31) ALDH1A1ALOX15
SCHEMBL12390034 0.73 ALDH1A1 (0.31) ALDH1A1ALOX15
SCHEMBL3544456 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331690-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF EYBNA TECHNOLOGIES LTD. (IL) 2023-10-19 US claimed
EP-4237416-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF Bar Ilan University (IL) 2023-09-06 EP claimed
WO-2022091098-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF BAR-ILAN UNIVERSITY (IL) 2022-05-05 WO claimed
US-20230331690-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF EYBNA TECHNOLOGIES LTD. (IL) 2023-10-19 US disclosed
EP-4237416-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF Bar Ilan University (IL) 2023-09-06 EP disclosed
WO-2022091098-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF BAR-ILAN UNIVERSITY (IL) 2022-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331690-A1 THC DERIVATIVES, ORAL DOSAGE FORMS COMPRISING SAME, USES THEREOF FOR TREATING DISEASES AND DISORDERS AND SYNTHESIS THEREOF CNR2, CNR1, UGT1A10 LMNA 3918/4885CES2 1175/4885ALDH1A1 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.