Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29618251 | 1.00 | PAX8 (0.56) | PAX8L3MBTL1UBE2NTRPV1ALOX12 | |
| SCHEMBL276426 | 0.85 | METAP2 (0.55) | TRPV1ALOX12ALDH1A1LMNAMMP2 | |
| Hydrochloric Acid SCHEMBL28754132 | 0.84 | METAP2 (0.53) | TRPV1ALOX12ALDH1A1LMNAMMP2 | |
| Trifluoroacetic Acid SCHEMBL28386678 | 0.81 | PARP1 (0.51) | L3MBTL1 | |
| Thiourea SCHEMBL3241360 | 0.78 | METAP2 (0.47) | TRPV1ALOX12ALDH1A1LMNAMMP2 | |
| Trifluoroacetic Acid SCHEMBL30618080 | 0.77 | L3MBTL1 (0.44) | PAX8L3MBTL1UBE2NTRPV1ALDH1A1 | |
| Quinazoline SCHEMBL561027 | 0.76 | EGFR (0.67) | ALOX12ALDH1A1LMNAMMP2CHRM1 | |
| Quinazoline SCHEMBL27562308 | 0.76 | EGFR (0.67) | PAX8L3MBTL1UBE2NALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30259961 | 0.76 | PAX8 (0.38) | PAX8L3MBTL1UBE2NTRPV1APAF1 | |
| SCHEMBL11798326 | 0.74 | TSHR (0.51) | L3MBTL1ALOX12ALDH1A1LMNAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724847-A | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives | 拜耳知识产权有限责任公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-108774232-B | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives | 拜耳知识产权有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-105254634-B | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives useful in the treatment of hyperproliferative diseases and angiogenesis-related diseases | 拜耳知识产权有限责任公司 | 2022-05-27 | — | — | CN | disclosed |