Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 8/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847177 | 0.85 | NOX1 (0.42) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL7072232 | 0.83 | MAOA (0.62) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL2495874 | 0.81 | NOX1 (0.52) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| Bromide SCHEMBL2586940 | 0.79 | NOX1 (0.51) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL4705856 | 0.77 | NOX1 (0.47) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL28098597 | 0.74 | DRD2 (0.37) | MEN1KMT2ADRD2HTR2AHTR7 | |
| SCHEMBL18018993 | 0.72 | NOX1 (0.46) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL9395281 | 0.70 | MAOA (0.68) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL28640004 | 0.69 | NOX1 (0.43) | NOX1L3MBTL1MEN1ADRA2AADRA2B | |
| SCHEMBL10980556 | 0.68 | ALOX5 (0.37) | SNCABCHESLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109329-A1 | TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS | ALIONYX ENERGY SYSTEMS (US) | 2022-05-27 | — | — | WO | disclosed |