SCHEMBL2495874

SCHEMBL2495874

CN1c2ccc(Br)cc2Sc2cc(Br)ccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 8/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ADRA2A P08913 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
CHRM3 P20309 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2C P28335 1/20 0.50
SLC6A4 P31645 1/20 0.50
DRD3 P35462 1/20 0.50
HTR2B P41595 1/20 0.50
MAOA P21397 1/20 0.50
SNCA P37840 5/20 0.46
DRD2 P14416 1/20 0.46
HTR2A P28223 1/20 0.46
HTR7 P34969 1/20 0.46
HTR6 P50406 1/20 0.46
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2586940 0.98 NOX1 (0.51) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL4705856 0.91 NOX1 (0.47) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL18018993 0.89 NOX1 (0.46) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL28640004 0.85 NOX1 (0.43) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL10923531 0.82 NOX1 (0.41) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL32682904 0.81 NOX1 (0.41) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL29619482 0.81 NOX1 (0.43) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL1984394 0.80 NOX1 (0.70) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL9395281 0.79 MAOA (0.68) NOX1L3MBTL1MEN1KMT2AADRA2A
SCHEMBL12073897 0.79 DRD2 (0.53) NOX1MEN1KMT2AADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed
WO-2022109329-A1 TRICYCLIC COMPOUNDS AND RELATED COMPOSITIONS, ZINC ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS ALIONYX ENERGY SYSTEMS (US) 2022-05-27 WO disclosed
US-RE48859-E1 Rechargeable lithium-ion cell BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2021-12-21 US disclosed
CN-110429279-B Organic anode material of lithium ion battery and application thereof 华中科技大学 2021-05-18 CN disclosed
CN-112646131-A Organic porous polymer and preparation method and application thereof 华南理工大学 2021-04-13 CN disclosed
CN-107078345-B Rechargeable lithium ion battery comprising redox shuttle additive 密歇根州立大学理事会 2020-03-20 CN disclosed
US-20190305381-A1 Rechargeable Lithium-ion Cell BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2019-10-03 US disclosed
US-10249910-B2 Rechargeable lithium-ion cell BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2019-04-02 US disclosed
EP-1817806-B1 PHENOTHAZINES-S-OXIDES AND S,S-DIOXIDES AS hole and excitonblockers for OLEDs BASF SE (DE) 2014-07-30 EP disclosed
US-20130230771-A1 Rechargeable metal or metal-ion cell UNIVERSITE JOSEPH FOURIER (FR) 2013-09-05 US disclosed
US-20130230771-A1 Rechargeable metal or metal-ion cell UNIVERSITE JOSEPH FOURIER (FR) 2013-09-05 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
EP-1817805-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
EP-1817806-A1 PHENOTHAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
WO-2006056416-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed
WO-2006056465-A1 PHENOTHIAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 NOX1 211/4885L3MBTL1 4489/4885MEN1 1625/4885
US-10249910-B2 Rechargeable lithium-ion cell SLC8A1, SLC9A2, SLC9A1 NOX1 1136/4885L3MBTL1 1392/4885MEN1 1234/4885
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds PPOX, SMOX, SORD NOX1 458/4885L3MBTL1 2540/4885MEN1 4804/4885
US-20190305381-A1 Rechargeable Lithium-ion Cell SLC9A1, SLC8A1, SLC9A2 NOX1 774/4885L3MBTL1 1860/4885MEN1 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.