Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619622 | 1.00 | TACR1 (0.43) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28710056 | 0.87 | TACR1 (0.36) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28966319 | 0.85 | KMT2A (0.59) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL28696415 | 0.84 | PTGS2 (0.34) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL24113156 | 0.84 | GPR84 (0.52) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL1196810 | 0.84 | GPR84 (0.52) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL30310656 | 0.84 | GPR84 (0.52) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28712063 | 0.83 | TACR1 (0.36) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL2013301 | 0.83 | MTNR1A (0.58) | TACR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL25288578 | 0.83 | NR4A2 (0.53) | TACR1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |