Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2956544 | 0.87 | TSHR (0.40) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL1774798 | 0.85 | GABRP (0.39) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Acetic Acid SCHEMBL5698774 | 0.83 | TSHR (0.46) | FFAR3TSHRKDM4E | |
| SCHEMBL2950666 | 0.81 | GABRP (0.37) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL2941882 | 0.81 | GABRP (0.37) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL2941887 | 0.81 | GABRP (0.37) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL25350353 | 0.81 | TSHR (0.39) | LMNATSHRKDM4E | |
| SCHEMBL2951141 | 0.81 | TDP1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Palmitic Acid SCHEMBL31053068 | 0.81 | GPR84 (0.65) | LMNACYP1A2TSHROR51E2SLC22A6 | |
| Myristic Acid SCHEMBL31053069 | 0.81 | GPR84 (0.65) | LMNACYP1A2TSHROR51E2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104692709-B | The EIFS preparation of rain resistance with raising | 陶氏环球技术有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-104136472-B | CARBOXYL GROUP CONTAINING ACRYLIC RDP AND DRY MIX CEMENT FORMULATIONS CONTAINING THEM | 陶氏环球技术有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-7766978-B2 | Acidic hair dyeing method | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | H1-0, MRM1, H1-4 | EGLN1 982/4885LMNA 1060/4885ALKBH5 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.