Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333891 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTPKMCES2 | |
| SCHEMBL381027 | 0.83 | NPC1 (0.44) | ALDH1A1HPGDMAPTPKMCES2 | |
| SCHEMBL16955913 | 0.83 | SLC6A4 (0.39) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL286942 | 0.81 | HTT (0.53) | HPGDMAPTCES2CES1MAOB | |
| SCHEMBL30523532 | 0.81 | HTT (0.53) | HPGDMAPTCES2CES1MAOB | |
| SCHEMBL29669896 | 0.80 | CES2 (0.67) | MAPTPKMCES2CES1MAOB | |
| SCHEMBL75801 | 0.80 | CES2 (0.67) | MAPTPKMCES2CES1MAOB | |
| SCHEMBL3022646 | 0.80 | MAPT (0.47) | ALDH1A1HPGDMAPTPKMS100A4 | |
| SCHEMBL356759 | 0.79 | KIF11 (0.49) | CES2CES1MAOBHDAC1HDAC6 | |
| SCHEMBL321581 | 0.79 | CES2 (0.43) | ALDH1A1MAPTCES2CES1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248510-B | Salts of 2-fluoro-N-methyl-4- [7- (quinolin-6-ylmethyl) imidazo [1,2-b ] [1,2,4] triazin-2-yl ] benzamide and methods for preparing same | 因西特控股公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-119233976-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118679160-A | BRM targeting compounds and related methods of use | 阿维纳斯运营公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118488950-A | ENPP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114555597-B | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-4298098-A1 | SULFONYL BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS | Ascentage Pharma (Suzhou) Co., Ltd. (CN) | 2024-01-03 | — | — | EP | disclosed |
| EP-3802550-B1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INST NAT SANTE RECH MED (FR) | 2023-12-27 | — | — | EP | disclosed |
| CN-114835704-B | Sulfonylbenzamide derivatives as BCL-2 inhibitors | 苏州亚盛药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-112236433-B | Novel compounds | 国家医疗保健研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-115361948-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-11-18 | — | — | CN | disclosed |
| EP-4041732-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| WO-2022161496-A1 | SULFONYL BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2022-08-04 | — | — | WO | disclosed |
| CN-114835704-A | Sulfonylbenzamide derivatives as BCL-2 inhibitors | 苏州亚盛药业有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114555597-A | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2022-05-27 | — | — | CN | disclosed |