Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307955 | 1.00 | BCHE (0.35) | BCHECYP11B2CYP19A1ACHEMAPT | |
| SCHEMBL5233554 | 0.94 | ACHE (0.37) | BCHECYP11B2CYP19A1ACHETBXAS1 | |
| SCHEMBL29429214 | 0.94 | ACHE (0.37) | BCHECYP11B2CYP19A1ACHETBXAS1 | |
| Carbamic Acid SCHEMBL16823528 | 0.89 | KDM4E (0.41) | BCHECYP11B2MAPTKDM4ETBXAS1 | |
| SCHEMBL29550114 | 0.87 | — | — | |
| SCHEMBL157325 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29651204 | 0.85 | ALDH1A1 (0.35) | BCHEACHEKDM4ECYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31159090 | 0.85 | ALDH1A1 (0.35) | BCHEACHEKDM4ECYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27985804 | 0.85 | ALDH1A1 (0.35) | BCHEACHEKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL28659623 | 0.82 | CYP19A1 (0.32) | CYP19A1ACHETBXAS1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | claimed |
| CN-110894198-B | Xanthine compound and preparation method and application thereof | 齐鲁制药有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114539154-A | Method for efficiently preparing multi-substituted pyrazole derivatives in aqueous phase | 湖北科技学院 | 2022-05-27 | — | — | CN | claimed |
| US-12378249-B2 | Isoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| EP-4532408-A1 | CATALYTIC SYSTEM FOR STORING AND RELEASING OF HYDROGEN FROM LIQUID ORGANIC HYDROGEN CARRIERS | Umicore AG & Co. KG (DE) | 2025-04-09 | — | — | EP | disclosed |
| CN-116478129-B | Quinoline compound and use thereof | 深圳默元生物科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-111201021-B | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118496221-A | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| CN-116478129-A | Quinoline compound and use thereof | 深圳默元生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | disclosed |
| CN-113264816-B | Spiro [ cyclopropane-1, 2' -indene ] -1',3' -diketone derivative and synthetic method thereof | 湖北科技学院 | 2023-03-24 | — | — | CN | disclosed |
| CN-110894198-B | Xanthine compound and preparation method and application thereof | 齐鲁制药有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-114539154-A | Method for efficiently preparing multi-substituted pyrazole derivatives in aqueous phase | 湖北科技学院 | 2022-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378249-B2 | Isoquinoline compounds and uses thereof | HIPK1, HPGDS, IP6K1 | BCHE 3222/4885CYP11B2 1391/4885CYP19A1 1907/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | BCHE 3468/4885CYP11B2 206/4885CYP19A1 61/4885 |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | PHKG1, MAP4K5, HIPK1 | BCHE 3370/4885CYP11B2 1790/4885CYP19A1 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.