Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.38 |
| ▸ | TUBB | P07437 | 6/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939446 | 1.00 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28733766 | 0.89 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29620915 | 0.89 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22926108 | 0.87 | CASP3 (0.43) | HDAC4HDAC1CHEK1GRM5 | |
| SCHEMBL22925955 | 0.83 | CASP3 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29620907 | 0.81 | MEN1 (0.40) | TRPA1CHEK1MEN1NPC1MAPT | |
| SCHEMBL28733613 | 0.81 | MEN1 (0.40) | TRPA1CHEK1MEN1NPC1MAPT | |
| SCHEMBL31013365 | 0.80 | CYP3A4 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22925938 | 0.79 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28939251 | 0.79 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |