SCHEMBL29620937

SCHEMBL29620937

Nc1ncc(-c2ccc(F)c(F)c2)o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.39
CYP17A1 P05093 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
SNCA P37840 1/20 0.38
NOTUM Q6P988 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
KMT2A Q03164 1/20 0.37
KLK7 P49862 1/20 0.36
USP7 Q93009 1/20 0.36
ALOX5AP P20292 2/20 0.36
FEN1 P39748 2/20 0.36
CYP1A2 P05177 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22925563 1.00 ABCB1 (0.39) ABCB1CYP17A1CYP11B1CYP11B2SNCA
SCHEMBL29620969 0.82 KIF11 (0.53) CYP11B1CYP11B2
SCHEMBL22925795 0.82 KIF11 (0.53) CYP11B1CYP11B2
SCHEMBL22925714 0.79 RAB9A (0.53) NOTUMRAB9AMEN1MITFKMT2A
SCHEMBL29620960 0.79 NOTUM (0.40) ABCB1CYP17A1CYP11B1CYP11B2SNCA
SCHEMBL14638175 0.79 NOTUM (0.40) ABCB1CYP17A1CYP11B1CYP11B2SNCA
SCHEMBL20242220 0.77 TAAR1 (0.46) NOTUMMEN1KMT2AKDM4E
SCHEMBL4534098 0.77 RAB9A (0.44) RAB9AMEN1MITFKMT2ACYP1A2
SCHEMBL20241503 0.76 SIRT1 (0.39) SNCANOTUMRAB9AMEN1MITF
SCHEMBL29243091 0.75 ABCB1 (0.40) ABCB1CYP17A1CYP11B1CYP11B2SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450281-A Inhibitor compounds 辛塞拉治疗私人有限公司 2022-05-06 CN disclosed