Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638175 | 1.00 | NOTUM (0.40) | NOTUMABCB1SNCARPA1RAB9A | |
| SCHEMBL15115338 | 0.85 | MAPT (0.42) | SNCAKMO | |
| SCHEMBL22925797 | 0.82 | CYP11B2 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL3638292 | 0.79 | NPC1 (0.53) | NOTUMRAB9ACYP1A2NPC1KDM4E | |
| SCHEMBL1218609 | 0.79 | NOTUM (0.59) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL14637955 | 0.79 | ALOX5AP (0.39) | NOTUMKMO | |
| SCHEMBL22925563 | 0.79 | ABCB1 (0.39) | NOTUMABCB1SNCARAB9ACYP1A2 | |
| SCHEMBL29620937 | 0.79 | ABCB1 (0.39) | NOTUMABCB1SNCARAB9ACYP1A2 | |
| SCHEMBL9954595 | 0.77 | GABRP (0.46) | NOTUMKDM4EVCP | |
| SCHEMBL23539672 | 0.76 | VCP (0.55) | NOTUMRAB9ANPC1VCPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |