Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | VCP | P55072 | 3/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620901 | 0.85 | TRPV1 (0.54) | TLR7KDRVCPP2RY1TRPV1 | |
| SCHEMBL29621004 | 0.82 | ACHE (0.49) | DHODHTLR7KDRFLT1 | |
| SCHEMBL22925921 | 0.77 | VCP (0.46) | KDRVCPTRPV1FLT1FLT4 | |
| SCHEMBL29620940 | 0.77 | VCP (0.46) | KDRVCPTRPV1FLT1FLT4 | |
| SCHEMBL22925920 | 0.72 | KDR (0.47) | KDRVCPTRPV1FLT1FLT4 | |
| SCHEMBL29620883 | 0.72 | KDR (0.47) | KDRVCPTRPV1FLT1FLT4 | |
| SCHEMBL28939252 | 0.71 | KDR (0.42) | KDRTRPV1FLT1FLT4IMPDH2 | |
| SCHEMBL29620896 | 0.71 | TRPV1 (0.52) | KDRVCPTRPV1FLT1FLT4 | |
| SCHEMBL28733810 | 0.70 | IMPDH2 (0.44) | DHODHKDRVCPFLT1FLT4 | |
| SCHEMBL29620982 | 0.70 | IMPDH2 (0.44) | DHODHKDRVCPFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |