Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803459 | 1.00 | HCAR2 (0.59) | HCAR2CA12CA1CA2CA9 | |
| SCHEMBL2962180 | 0.94 | CA12 (0.52) | HCAR2CA12CA1CA2CA9 | |
| SCHEMBL28803458 | 0.94 | CA12 (0.52) | HCAR2CA12CA1CA2CA9 | |
| SCHEMBL3169558 | 0.80 | THRB (0.53) | HCAR2CA12CA1CA2CA9 | |
| SCHEMBL27576539 | 0.79 | HCAR2 (0.49) | HCAR2LMNAMAPTMDM4MDM2 | |
| SCHEMBL3235281 | 0.78 | HCAR2 (0.54) | HCAR2LMNAMAPTMDM4MDM2 | |
| SCHEMBL11385770 | 0.77 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11244962 | 0.77 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11244967 | 0.77 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| Cyanide SCHEMBL28037734 | 0.76 | THRB (0.49) | HCAR2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763263-B2 | Skin external agents and drugs | KAO CORPORATION (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1249237-B1 | Topical cosmetic and pharmaceutical composition comprising specific alkoxylated diester of fumaric acid | KAO CORP (JP) | 2007-07-18 | — | — | EP | disclosed |
| US-20060177408-A1 | Skin external agents and drugs | KANEBO COSTMETICS INC. | 2006-08-10 | — | — | US | disclosed |
| US-7037489-B2 | Skin external agents and drugs | KANEBO COSMETICS, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20030185786-A1 | Skin external agents and drugs | KAO CORPORATION (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1249237-A1 | SKIN EXTERNAL AGENTS AND DRUGS | Kanebo Limited (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177408-A1 | Skin external agents and drugs | CUTA, F12, NFE2 | HCAR2 452/4885CA12 367/4885CA1 1079/4885 |
| US-20030185786-A1 | Skin external agents and drugs | AREG, RARG, FRG1 | HCAR2 191/4885CA12 1743/4885CA1 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.