SCHEMBL29622892

SCHEMBL29622892

O=C(CNCc1ccc2c(c1)OCO2)N1CCCC1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.60
DPP7 Q9UHL4 3/20 0.59
LTA4H P09960 1/20 0.56
ALDH1A1 P00352 3/20 0.51
HPGD P15428 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29622860 0.99 TRPV1 (0.62) TRPV1DPP7LTA4HALDH1A1HPGD
SCHEMBL29540555 0.84 DPP7 (0.59) TRPV1DPP7ALDH1A1HPGD
SCHEMBL29384564 0.83 DPP7 (0.58) TRPV1DPP7ALDH1A1HPGD
SCHEMBL2043178 0.80 MEN1 (0.61) DPP7ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL9425805 0.80 TRPV1 (0.81) TRPV1ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL8843511 0.79 DPP7 (0.59) DPP7ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL9425973 0.78 TRPV1 (0.83) TRPV1ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL18313841 0.77 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL6295177 0.76 MEN1 (0.59) DPP7ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL109279 0.76 ALDH1A1 (0.67) DPP7ALDH1A1HPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119986166-A Electrical sensor assembly G&W电气公司 2025-05-13 CN disclosed
CN-113227802-B Electrical sensor assembly G&W电气公司 2025-02-11 CN disclosed
US-20240376058-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC 2024-11-14 US disclosed
US-20240336700-A1 ANTIGEN-BINDING POLYPEPTIDES DIRECTED AGAINST CD38 UNIVERSITY MEDICAL CENTER HAMBURG-EPPENDORF (DE) 2024-10-10 US disclosed
US-12018088-B2 Antigen-binding polypeptides directed against CD38 UNIVERSITY MEDICAL CENTER HAMBURG-EPPENDORF (DE) 2024-06-25 US disclosed
US-20240196931-A1 BOTANICAL SUPPLEMENT AND METHOD FOR PREVENTING DISEASES, PROMOTING GROWTH AND SURVIVAL OF AN ANIMAL BY USING THE SAME ACADEMIA SINICA (TW) 2024-06-20 US disclosed
US-11912668-B2 GCN2 and perk kinase inhibitors and methods of use thereof DECIPHERA PHARMACEUTICALS, LLC (US) 2024-02-27 US disclosed
CN-117599850-A Nano composite material of fullerene/photosensitizer, preparation method and application thereof 中国科学院化学研究所 2024-02-27 CN disclosed
US-11774481-B2 Electrical sensor assembly G & W ELECTRIC COMPANY (US) 2023-10-03 US disclosed
EP-4247795-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF Deciphera Pharmaceuticals, LLC (US) 2023-09-27 EP disclosed
CN-113603877-B Functionalized diblock copolymer, preparation method and application thereof 亭创生物科技(上海)有限公司 2023-07-25 CN disclosed
CN-114990168-B Composition prepared by fermenting sour cherry and having good health care function and application of composition in health field 灶灶科技有限公司 2023-05-26 CN disclosed
CN-111662341-B Method for oxidative depolymerization of lignin and application thereof 东南大学 2023-01-31 CN disclosed
US-20220357382-A1 ELECTRICAL SENSOR ASSEMBLY G & W ELECTRIC COMPANY 2022-11-10 US disclosed
CN-114990168-A Composition prepared by fermenting sour cherry and having good health care function and application thereof in health field 清枫链食苏打饮品(吉林)有限公司 2022-09-02 CN disclosed
US-20220274934-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC 2022-09-01 US disclosed
US-11346876-B2 Electrical sensor assembly G & W ELECTRIC COMPANY (US) 2022-05-31 US disclosed
WO-2022109001-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC (US) 2022-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376058-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF EIF2AK4, GCN1, EEF2K TRPV1 4394/4885DPP7 1895/4885LTA4H 3770/4885
US-20220274934-A1 GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF EIF2AK4, GCN1, EEF2K TRPV1 4394/4885DPP7 1895/4885LTA4H 3770/4885
US-11912668-B2 GCN2 and perk kinase inhibitors and methods of use thereof EIF2AK4, GCN1, MAPKAPK2 TRPV1 4049/4885DPP7 3787/4885LTA4H 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.