Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29623703 | 0.84 | MAPT (0.47) | LMNAGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21932070 | 0.79 | SMN1; SMN2 (0.41) | CYP3A4ALDH1A1SMN1; SMN2MAPK1MMP2 | |
| SCHEMBL21999069 | 0.79 | MMP2 (0.37) | GAANPC1SMN1; SMN2MMP2MMP9 | |
| SCHEMBL5626036 | 0.78 | MMP2 (0.39) | TSHRCYP3A4ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28033051 | 0.76 | LMNA (0.58) | LMNATSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2994448 | 0.74 | ALDH1A1 (0.44) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5624601 | 0.74 | MMP2 (0.36) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL3150048 | 0.73 | CYP3A4 (0.42) | LMNATSHRCYP3A4CYP2C9GAA | |
| SCHEMBL6327814 | 0.73 | MMP2 (0.43) | LMNATSHRCYP1A2CYP3A4GAA | |
| SCHEMBL6082056 | 0.72 | TSHR (0.56) | LMNATSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986468-A1 | ANTIB0DY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | Synthis Therapeutics, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |