Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909632 | 0.88 | FABP4 (0.64) | FABP4FABP3FABP5CLCN2MEN1 | |
| Hydrochloric Acid SCHEMBL27966132 | 0.84 | CDC7 (0.50) | SIRT2SIRT1MKNK2PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL27966298 | 0.84 | CDC7 (0.50) | SIRT2SIRT1MKNK2PDCD1CD274 | |
| SCHEMBL27703792 | 0.83 | FABP4 (0.51) | FABP4SIRT2SIRT1PDCD1CD274 | |
| SCHEMBL3441356 | 0.82 | AGTR1 (0.54) | SIRT2MKNK1MKNK2PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL5389527 | 0.80 | AGTR1 (0.53) | SIRT2MKNK1MKNK2PDCD1CD274 | |
| SCHEMBL25343189 | 0.80 | SIRT2 (0.54) | FABP4SIRT2SIRT1PDCD1CD274 | |
| SCHEMBL29546145 | 0.80 | SIRT2 (0.54) | FABP4SIRT2SIRT1PDCD1CD274 | |
| SCHEMBL27214460 | 0.78 | BCAT2 (0.63) | FABP4SIRT2SIRT1PDCD1CD274 | |
| SCHEMBL29623796 | 0.78 | KDM4E (0.47) | FABP4MKNK1MKNK2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002518-A1 | NOVEL 2,4-DIFLUOROBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | DONG HWA PHARM. IND. CO., LTD. (KR) | 2003-01-09 | — | — | WO | claimed |