SCHEMBL31257072

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CO)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.48

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MAGI3	Q5TCQ9	1/20	0.48

▸	BACE1	P56817	2/20	0.46

▸	GLP1R	P43220	8/20	0.41

▸	CRHR1	P34998	1/20	0.39

▸	CRHR2	Q13324	1/20	0.39

▸	CALCR	P30988	4/20	0.38

▸	VIPR1	P32241	1/20	0.38

▸	VIPR2	P41587	1/20	0.38

▸	CCNA2	P20248	1/20	0.38

▸	CDK2	P24941	1/20	0.38

▸	CCNA1	P78396	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257073	0.93	MAGI3 (0.44)	MAGI3BACE1GLP1R
SCHEMBL29805325	0.90	BACE1 (0.44)	MAGI3BACE1GLP1R
SCHEMBL31663833	0.89	BACE1 (0.49)	MAGI3BACE1GLP1R
SCHEMBL31256985	0.87	GLP1R (0.45)	BACE1GLP1RVIPR1VIPR2
SCHEMBL30338373	0.87	BACE1 (0.46)	MAGI3BACE1GLP1RCRHR1CRHR2
SCHEMBL31257083	0.87	BACE1 (0.43)	MAGI3BACE1GLP1R
SCHEMBL31256975	0.86	BACE1 (0.42)	BACE1GLP1R
SCHEMBL31257065	0.86	MAGI3 (0.42)	MAGI3BACE1GLP1R
SCHEMBL29994497	0.86	BACE1 (0.48)	BACE1GLP1RVIPR1VIPR2
SCHEMBL29624554	0.85	BACE1 (0.43)	MAGI3BACE1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed