Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28727045 | 1.00 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10CYP2C9 | |
| SCHEMBL3593457 | 0.83 | NQO1 (0.54) | KDM4EALDH1A1HPGDSLC2A1CA12 | |
| SCHEMBL24953219 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL617928 | 0.82 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL7287472 | 0.80 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9561825 | 0.80 | ALDH1A1 (0.96) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL4428250 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP2C9 | |
| SCHEMBL27503589 | 0.78 | HSD17B10 (0.63) | KDM4EALDH1A1HPGDHSD17B10SLC2A1 | |
| SCHEMBL12185684 | 0.77 | LTA4H (0.50) | KDM4EALDH1A1HPGDSLC2A1 | |
| SCHEMBL27834259 | 0.75 | SLC2A1 (0.56) | KDM4EALDH1A1HPGDSLC2A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |