Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515251 | 0.89 | SLC2A1 (0.44) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL12185684 | 0.88 | LTA4H (0.50) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL9477688 | 0.85 | SLC2A1 (0.54) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL24953221 | 0.85 | SLC2A1 (0.48) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL29625652 | 0.83 | KDM4E (0.69) | SLC2A1ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL28727045 | 0.83 | KDM4E (0.69) | SLC2A1ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL8406889 | 0.83 | NQO1 (0.50) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL30975091 | 0.83 | PDE4A (0.64) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL4439625 | 0.83 | ALDH1A1 (0.50) | NQO1SLC2A1ALDH1A1HPGDKDM4E | |
| SCHEMBL30975093 | 0.83 | PDE4A (0.64) | NQO1SLC2A1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714167-B2 | Catalytic asymmetric epoxidation | UNIVERSITY OF CHICAGO (US) | 2010-05-11 | — | — | US | disclosed |
| US-7714167-B2 | Catalytic asymmetric epoxidation | UNIVERSITY OF CHICAGO (US) | 2010-05-11 | — | — | US | disclosed |
| US-7714167-B2 | Catalytic asymmetric epoxidation | UNIVERSITY OF CHICAGO (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1706205-B1 | A CATALYTICAL ASYMMETRIC EPOXIDATION | UNIV CHICAGO (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1706205-B1 | A CATALYTICAL ASYMMETRIC EPOXIDATION | UNIV CHICAGO (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203347-A1 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-08-30 | — | — | US | disclosed |
| US-7202371-B2 | Catalytic asymmetric epoxidation | THE UNIVERSITY OF CHICAGO (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1706205-A1 | A CATALYTIC ASYMMETRIC EPOXIDATION | University of Chicago (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005072868-A1 | A CATALYTIC ASYMMETRIC EPOXIDATION | UNIVERSITY OF CHICAGO (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050159607-A1 | Catalytic asymmetric epoxidation | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203347-A1 | Catalytic asymmetric epoxidation | DUOX1, DUOX2, EPHX2 | NQO1 141/4885SLC2A1 4309/4885ALDH1A1 320/4885 |
| US-20050159607-A1 | Catalytic asymmetric epoxidation | DUOX1, DUOX2, EPHX2 | NQO1 141/4885SLC2A1 4309/4885ALDH1A1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.