Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14569798 | 0.85 | SLC2A1 (0.39) | SLC2A1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7709361 | 0.84 | MAPT (0.37) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29560409 | 0.83 | MAPT (0.49) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL635407 | 0.83 | MAPT (0.49) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20563974 | 0.81 | MAPT (0.37) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31375043 | 0.80 | MAPT (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL20563667 | 0.80 | NCEH1 (0.47) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11889275 | 0.80 | LMNA (0.46) | SLC2A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6233321 | 0.80 | MAPT (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL1056365 | 0.79 | ALDH1A1 (0.46) | HSD17B10L3MBTL1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |