SCHEMBL6233321

SCHEMBL6233321

O=S(=O)(Oc1ccc2ccccc2c1Br)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NCEH1 Q6PIU2 6/20 0.46
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 2/20 0.43
RXFP1 Q9HBX9 3/20 0.42
PRNP P04156 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
HPGD P15428 2/20 0.42
CYP2C9 P11712 1/20 0.42
HTT P42858 1/20 0.42
LMNA P02545 1/20 0.41
POLB P06746 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31375043 1.00 MAPT (0.46) MAPTL3MBTL1NCEH1RAB9ASMN1; SMN2
SCHEMBL7709361 0.86 MAPT (0.37) MAPTL3MBTL1NCEH1RAB9ASMN1; SMN2
SCHEMBL29560409 0.84 MAPT (0.49) MAPTL3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL635407 0.84 MAPT (0.49) MAPTL3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL15297711 0.83 DRD2 (0.33)
SCHEMBL3418568 0.83 CYP19A1 (0.44) MAPTL3MBTL1NCEH1
SCHEMBL20563974 0.83 MAPT (0.37) MAPTL3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL13233215 0.82 NCEH1 (0.48) L3MBTL1NCEH1SMN1; SMN2RXFP1LMNA
SCHEMBL20563667 0.81 NCEH1 (0.47) MAPTL3MBTL1NCEH1RAB9ASMN1; SMN2
SCHEMBL11889275 0.81 LMNA (0.46) MAPTL3MBTL1NCEH1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843667-A Asymmetric fulvene- [ b ] -condensed BODIPY fluorescent compound and preparation method thereof 中国计量大学 2024-04-09 CN disclosed
US-11800785-B2 Material for organic device and organic electroluminescent device using the same KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-10-24 US disclosed
US-11800785-B2 Material for organic device and organic electroluminescent device using the same KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-10-24 US disclosed
US-20220006012-A1 MATERIAL FOR ORGANIC DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-01-06 US disclosed
CN-113677731-A Graphene nanoribbons and methods of making the same 田冈化学工业株式会社 2021-11-19 CN disclosed
US-11174389-B2 Phosphole compound NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2021-11-16 US disclosed
WO-2020184625-A1 GRAPHENE NANORIBBON AND METHOD FOR PRODUCING SAME 国立大学法人東海国立大学機構 2020-09-17 WO disclosed
US-20190264031-A1 PHOSPHOLE COMPOUND NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2019-08-29 US disclosed
EP-3098227-B1 PHOSPHOLE COMPOUND AND FLUORESCENT DYE CONTAINING SAME UNIV NAGOYA NAT UNIV CORP (JP) 2018-10-24 EP disclosed
US-9951094-B2 Phosphole compound and fluorescent dye containing the same NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2018-04-24 US disclosed
EP-3098227-A1 PHOSPHOLE COMPOUND AND FLUORESCENT DYE CONTAINING SAME National University Corporation Nagoya University (JP) 2016-11-30 EP disclosed
US-20160333037-A1 PHOSPHOLE COMPOUND AND FLUORESCENT DYE CONTAINING THE SAME NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2016-11-17 US disclosed
US-9309174-B2 Polycyclic ring assembly compound and organic electroluminescent device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-9309174-B2 Polycyclic ring assembly compound and organic electroluminescent device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-20140264318-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-09-18 US disclosed
US-20140264318-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-09-18 US disclosed
WO-2013077142-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-05-30 WO disclosed
US-20100187512-A1 POLYCYCLIC RING ASSEMBLY COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2010-07-29 US disclosed
US-20100187512-A1 POLYCYCLIC RING ASSEMBLY COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2010-07-29 US disclosed
WO-2005000855-A1 PROCESS FOR THE PREPARATION OF ATROPISOMERIC ANALOGUES OF 4-AMINOPYRIDINE IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2005-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174389-B2 Phosphole compound AR, PHOSPHO1, NR2E3 MAPT 2828/4885L3MBTL1 2577/4885NCEH1 4407/4885
US-20160333037-A1 PHOSPHOLE COMPOUND AND FLUORESCENT DYE CONTAINING THE SAME PHOSPHO1, INPPL1, INPP5D MAPT 2448/4885L3MBTL1 3336/4885NCEH1 3520/4885
US-11800785-B2 Material for organic device and organic electroluminescent device using the same RER1, LEF1, CHRM1 MAPT 4476/4885L3MBTL1 27/4885NCEH1 1626/4885
US-20220006012-A1 MATERIAL FOR ORGANIC DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME RER1, LEF1, CHRM1 MAPT 4476/4885L3MBTL1 27/4885NCEH1 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.