SCHEMBL2962650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4177681	0.84	L3MBTL1 (0.40)	ALDH1A1LMNATSHRSMN1; SMN2CYP2C9
	SCHEMBL2955104	0.83	P2RX7 (0.43)	ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
	SCHEMBL2952792	0.82	L3MBTL1 (0.42)	ALDH1A1HSD17B10TSHRSMN1; SMN2CYP2C9
	SCHEMBL5771257	0.81	ELANE (0.32)	ALDH1A1HSD17B10NPSR1GAAPOLB
	SCHEMBL5772185	0.80	HIF1A (0.36)	ALDH1A1LMNATSHRSMN1; SMN2CYP2C9
	SCHEMBL5719350	0.77	ADORA2B (0.43)	ALDH1A1HSD17B10LMNASMN1; SMN2CYP2C9
	SCHEMBL5719315	0.77	TSHR (0.51)	ALDH1A1LMNATSHRSMN1; SMN2HTT
	SCHEMBL2964029	0.76	KMT2A (0.37)	ALDH1A1HSD17B10LMNASMN1; SMN2NPSR1
	SCHEMBL6409570	0.76	MAOB (0.38)	ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
	SCHEMBL23146029	0.76	KMT2A (0.41)	ALDH1A1TSHRHPGDCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.