Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23165184 | 1.00 | KEAP1 (0.38) | KEAP1NFE2L2PTPN11L3MBTL1ALOX5 | |
| SCHEMBL23164955 | 0.90 | ERN1 (0.40) | ERN1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2579330 | 0.87 | MEN1 (0.34) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29627234 | 0.81 | MPO (0.46) | PTPN11FABP3FABP4FABP5 | |
| SCHEMBL23164501 | 0.81 | MPO (0.46) | PTPN11FABP3FABP4FABP5 | |
| SCHEMBL18131171 | 0.77 | L3MBTL1 (0.32) | L3MBTL1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL23193787 | 0.77 | LMNA (0.41) | PTPN11L3MBTL1LMNAGAANPC1 | |
| SCHEMBL29627217 | 0.77 | LMNA (0.41) | PTPN11L3MBTL1LMNAGAANPC1 | |
| SCHEMBL18131220 | 0.73 | NPC1 (0.32) | NPC1 | |
| SCHEMBL18131189 | 0.73 | MAPT (0.34) | L3MBTL1LMNASMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466844-B | N- (1H-imidazol-2-yl) benzamide compound and pharmaceutical composition comprising same as active ingredient | 康佳诺医疗科技发展有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114466844-A | N- (1H-imidazol-2-yl) benzamide compounds and pharmaceutical compositions containing the same as active ingredient | 康佳诺医疗科技发展有限公司 | 2022-05-10 | — | — | CN | disclosed |