Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15751564 | 0.83 | HPGDS (0.36) | HSD17B2HSD17B1 | |
| SCHEMBL3077344 | 0.79 | HSD17B2 (0.52) | HSD17B2HSD17B1 | |
| SCHEMBL19178226 | 0.77 | HSD17B2 (0.51) | HSD17B2HSD17B1 | |
| SCHEMBL19616295 | 0.77 | HSD17B2 (0.54) | HSD17B2HSD17B1 | |
| SCHEMBL844968 | 0.77 | HSD17B2 (0.51) | HSD17B2HSD17B1 | |
| SCHEMBL19178227 | 0.74 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL3056728 | 0.73 | KDM4E (0.60) | HSD17B2HSD17B1 | |
| SCHEMBL15967178 | 0.73 | HSD17B2 (0.60) | HSD17B2HSD17B1 | |
| SCHEMBL6375741 | 0.73 | L3MBTL1 (0.53) | HSD17B2HSD17B1 | |
| SCHEMBL22867299 | 0.73 | HSD17B2 (0.54) | HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997096-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2024-08-28 | — | — | EP | disclosed |
| US-20220242876-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2022-08-04 | — | — | US | disclosed |
| EP-3997096-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220242876-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | HSD17B2 750/4885HSD17B1 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.