Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081670 | 0.86 | HSD17B2 (0.42) | HSD17B2HSD17B1 | |
| SCHEMBL3094841 | 0.86 | HSD17B2 (0.40) | HSD17B2HSD17B1 | |
| SCHEMBL22868076 | 0.86 | HSD17B2 (0.42) | HSD17B2HSD17B1 | |
| SCHEMBL3077344 | 0.83 | HSD17B2 (0.52) | HSD17B2HSD17B1 | |
| SCHEMBL3071478 | 0.83 | HSD17B2 (0.40) | HSD17B2HSD17B1 | |
| SCHEMBL4898548 | 0.83 | HSD17B2 (0.40) | HSD17B2HSD17B1 | |
| SCHEMBL19616295 | 0.81 | HSD17B2 (0.54) | HSD17B2HSD17B1 | |
| SCHEMBL19178226 | 0.81 | HSD17B2 (0.51) | HSD17B2HSD17B1 | |
| SCHEMBL19178227 | 0.78 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL29628486 | 0.77 | HSD17B2 (0.48) | HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360082-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2024-10-31 | — | — | US | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| EP-2635550-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE-DERIVATIVES | BAYER IP GMBH (DE) | 2016-01-27 | — | — | EP | claimed |
| US-9204640-B2 | 2-acyloxy-pyrrolin-4-ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | claimed |
| US-9198432-B2 | 1,2,4-triazolyl-substituted ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2681191-B1 | 2-ACYLOXY-PYRROLIN-4-ONES | BAYER IP GMBH (DE) | 2015-09-02 | — | — | EP | claimed |
| EP-2534147-B1 | SPIROHETEROCYCLIC-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-06-17 | — | — | EP | claimed |
| US-8946124-B2 | Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-02-03 | — | — | US | claimed |
| EP-3994125-B1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMA (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20240360082-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2024-10-31 | — | — | US | disclosed |
| US-20240299402-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11957687-B2 | Modulators of HSD17B13 and methods of use thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| EP-1982978-A1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | HSD17B2 3126/4885HSD17B1 3020/4885 |
| US-20240299402-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | HSD17B3, HSD17B11, HSD17B1 | HSD17B2 5/4885HSD17B1 3/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | HSD17B2 4644/4885HSD17B1 4494/4885 |
| US-11957687-B2 | Modulators of HSD17B13 and methods of use thereof | HSD17B3, HSD17B11, HSD17B1 | HSD17B2 5/4885HSD17B1 3/4885 |
| US-20240360082-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | PNPO, PDXK, PLPBP | HSD17B2 2882/4885HSD17B1 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.