Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878066 | 0.93 | SMN1; SMN2 (0.58) | SMYD3SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL19710364 | 0.92 | SMYD3 (0.61) | SMYD3SMN1; SMN2L3MBTL1 | |
| SCHEMBL21489887 | 0.92 | SMYD3 (0.61) | SMYD3SMN1; SMN2L3MBTL1 | |
| SCHEMBL3682800 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1NPC1RAB9AACKR3 | |
| SCHEMBL19710371 | 0.86 | SMYD3 (0.60) | SMYD3 | |
| SCHEMBL4435015 | 0.85 | SMN1; SMN2 (0.43) | SMYD3SMN1; SMN2L3MBTL1ACKR3KMT2A | |
| SCHEMBL27917155 | 0.79 | ALDH1A1 (0.52) | SMYD3SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL9651228 | 0.78 | SIGMAR1 (0.61) | L3MBTL1ACKR3 | |
| SCHEMBL5202785 | 0.75 | — | — | |
| SCHEMBL22372185 | 0.75 | MAPK14 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117546-A | ATP-binding cassette transport protein conditioning agent | 弗特克斯药品有限公司 | 2018-06-05 | — | — | CN | disclosed |
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7678915-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070010677-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20050209279-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919458-B2 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| EP-0868182-B1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 2003-09-03 | — | — | EP | disclosed |
| US-20030028029-A1 | Process for production of piperidine derivatives | BARCLAYS BANK PLC, AS THE COLLATERAL AGENT | 2003-02-06 | — | — | US | disclosed |
| US-6458958-B1 | PROCESS OF PREPARING A PIPERIDINE DERIVATIVE COMPOUND OF THE FORMULA: ACYLATING AN .ALPHA.,.ALPHA.-DISUBSTITUTED-METHYLBENZENE DERIVATIVE HAVING THE FORMULA: | ALBANY MOLECULAR RESEARCH, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6444824-B1 | ANTISEROTONINE AGENTS; SIDE EFFECT REDUCTION | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-03 | — | — | US | disclosed |
| US-6153754-A | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0868182-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0868182-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997023213-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | HPD, PTMA, HAAO | SMYD3 1206/4885SMN1; SMN2 2845/4885L3MBTL1 4045/4885 |
| US-20050209279-A1 | Process for production of piperidine derivatives | NR5A2, NR4A1, NR4A2 | SMYD3 725/4885SMN1; SMN2 3072/4885L3MBTL1 3769/4885 |
| US-20070010677-A1 | Process for production of piperidine derivatives | NR4A1, NR5A2, NR4A2 | SMYD3 668/4885SMN1; SMN2 3353/4885L3MBTL1 4065/4885 |
| US-20030028029-A1 | Process for production of piperidine derivatives | NR4A1, RCOR1, CBR1 | SMYD3 651/4885SMN1; SMN2 2554/4885L3MBTL1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.