Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.57 |
| ▸ | CA1 | P00915 | 10/20 | 0.57 |
| ▸ | CA12 | O43570 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871649 | 1.00 | CA2 (0.57) | CA2CA1CA12CA9CA14 | |
| SCHEMBL22014885 | 0.86 | NLRP3 (0.41) | CA2CA1CA12CA9NOS1 | |
| SCHEMBL30244073 | 0.86 | NLRP3 (0.41) | CA2CA1CA12CA9NOS1 | |
| SCHEMBL7130700 | 0.85 | LMNA (0.50) | CA2CA1NLRP3MAPT | |
| SCHEMBL12025007 | 0.85 | CA2 (0.61) | CA2CA1CA12CA9CA14 | |
| SCHEMBL12157465 | 0.83 | KIF11 (0.48) | CA2CA1NR1H3NLRP3 | |
| SCHEMBL12841398 | 0.83 | CA2 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL19943829 | 0.81 | NLRP3 (0.43) | CA2CA1NR1H3NLRP3MAPT | |
| SCHEMBL28009704 | 0.81 | CA2 (0.52) | CA2CA1CA12CA9CA14 | |
| SCHEMBL19475024 | 0.80 | APEX1 (0.45) | CA2CA1CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-B | Sulfonamide compound or salt thereof | 大鹏药品工业株式会社 | 2022-06-24 | — | — | CN | disclosed |